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Extra info for Attempts to Understand Metastasis Formation II: Regulatory Factors
Furthermore, the enhanced adhesion of tumor cells to endothelium was blocked in presence of the peptide Arg-Gly-Asp (GRGDS; LAURI et al. 1990; LAFRENIE et al. 1992), suggesting that the adhesion of cancer cells to activated endothelial cells may also be related to Arg-Gly-Asp (RGD)-dependent endothelial surface adhesion molecule. In these studies a relationship between vessel wall Iypoxygenase metabolites, adhesion molecule expression, and adhesion of tumor cells to endothelium is also suggested (BERTOMEU et al.
35 4 In Vitro Models for the Study of Angiogenesis .................................. 37 5 Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor .............. 39 6 Transforming Growth Factor-131 . . . . . . . . . . . . . . . . . . . . . . . 46 7 Other Cytokines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Interferon-a,. . . . . . . . . . . . . . . . . . . . . . . .
Integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80: 413-422 Bertomeu MC. Gallo S. Lauri D. Haas TA. Orr FW. Bastida E. Buchanan MR (1993) Interleukin 1-induced cancer celVendothelial cell adhesion in vitro and its relationship to metastasis in vivo: role of vessel wall 13-HODE synthesis and integrin expression. Clin Expl Metastasis 11: 243-250 Bevilacqua MP (1993) Endothelial-leukocyte adhesion molecules. Ann Rev Immunol 11: 767-804 Bevilacqua MP. Nelson RM (1993a) Endothelial-leukocyte adhesion molecules in inflammation and metastasis.