Astrocytes in Brain Aging and Neurodegeneration by Hyman M. Schipper

By Hyman M. Schipper

256 pages, sixty seven figures, 6 tables, hardcover This monograph is the 1st of its variety to concentration particularly at the position of astroglia in aging-related human neurodegenerative problems and experimental types of CNS senescence and degeneration. As such, this quantity within the Neuroscience Intelligence Unit sequence represents a unique and significant contribution to the elemental and scientific neuroscience literature. The chapters are grouped into 3 sections: I. Biology of Astrocytes. The chapters during this part will represent a accomplished dialogue of the identified services of astroglia within the mammalian CNS and the jobs those cells may possibly play within the pathophysiology of neurological issues. II. Astrocytes in Human mind Senescence and Neurodegenerative problems. during this part, the pathology of astrocytes and their putative roles in human CNS senescence and diverse neurodegenerative stipulations are coated in significant element. III. Experimental versions of Astrocyte Senescence: Implications for Neurodegenerative ! illness. during this ultimate part, experimental methods to the delineation of the function of astroglia in mind getting older and degeneration are defined. This e-book should still attraction greatly to uncomplicated neuroscientists drawn to a variety of elements of the biology of those cells in addition to to clinically-oriented investigators focused on the pathogenesis of the key human neurodegenerative problems.

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Kimelberg HK. Receptors on astrocytes—What possible functions. Neurochem Int 1995; 26:27-40. 87. Cornell-Bell AH, Finkbeiner SM, Cooper MS et al. Glutamate induces calcium in cultured astrocytes: Long-range glial signaling. Science 1990; 247:470-473. 88. Glaum SR, Miller RJ. Acute regulation of synaptic transmission by metabotropic glutamate receptors. In: Conn PJ, Patel J eds. The Metabotropic Glutamate Receptors. Totowa, NJ: Humana Press, 1994:147-172. 89. Deecher DC, Wilcox BD, Dave V et al.

Annual Rev Neurosci 1990; 13:441-474. 13. Duffy S, MacVicar BA. Voltage-dependent ionic channels in astrocytes. In: Murphy S, ed. Astrocytes, Pharmacology and Function. San Diego: Academic Press, 1993:137. 14. Kimelberg HK, Jalonen T, Walz W. Regulation of the brain microenvironment: Transmitters and ions. In: Murphy S, ed. Astrocytes, Pharmacology and Function. , 1993:193-228. 15. Sontheimer H. Voltage-dependent ion channels in glial cells. Glia 1994; 11:156-172. 16. Takumi T, Ishii T, Horio Y et al.

Ion channels in vertebrate glia. Annual Rev Neurosci 1990; 13:441-474. 13. Duffy S, MacVicar BA. Voltage-dependent ionic channels in astrocytes. In: Murphy S, ed. Astrocytes, Pharmacology and Function. San Diego: Academic Press, 1993:137. 14. Kimelberg HK, Jalonen T, Walz W. Regulation of the brain microenvironment: Transmitters and ions. In: Murphy S, ed. Astrocytes, Pharmacology and Function. , 1993:193-228. 15. Sontheimer H. Voltage-dependent ion channels in glial cells. Glia 1994; 11:156-172.

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